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November 11, 2025 Mitochondria dysfunction found in autism Center Brain & Cog Dev., Birkbeck College, London Source: Autism Open Access, 2016 View ONLINE or Download PDF This is one of many studies showing mitochondrial dysfunction (low quality and/or low number) is prevalent in children with Autism Spectrum Disorder (ASD)

doi: 10.1146/annurev-biochem-061516-045037 6

Polyamines: new cues in cellular signal transduction

Simultaneously, actin cytoskeleton rearrangements influence mitochondrial constriction sites, contact with the ER, and positioning near lysosomes, collectively shaping the likelihood that damaged mitochondria will undergo mitophagy versus progressing toward permeabilization and DAMP release